Cambridge journal ‘Disease Models and Mechanisms’ publish interview with Professor Lalita Ramakrishnan to coincide with World TB Day (WHO) Professor Lalita Ramakrishnan is at the forefront of modern tuberculosis (TB) research. She has developed vital tools, most notably a robust zebrafish model, to study this disease, leading to seminal discoveries uncovering bacterial and host interactions […]
£16million gift to support Europe’s largest heart and lung research centre
A Cambridge institute dedicated to improving cardiovascular and lung health has received a £16 million gift from Canadian entrepreneur and philanthropist Dr Victor Dahdaleh.
Underactive immune response may explain obesity link to COVID-19 severity
Individuals who are obese may be more susceptible to severe COVID-19 because of a poorer inflammatory immune response, say Cambridge scientists. Scientists at the Cambridge Institute of Therapeutic Immunology and Infectious Disease (CITIID) and Wellcome Sanger Institute showed that following SARS-CoV-2 infection, cells in the lining of the lungs, nasal cells, and immune cells in […]
Rare genetic disease may protect Ashkenazi Jews against TB
Department of Medicine Scientists may have solved the question of why Ashkenazi Jews are significantly more susceptible to a rare genetic disorder known as Gaucher disease – and the answer may help settle the debate about whether they are less susceptible to tuberculosis (TB).
A patient-centric modelling framework captures recovery from SARS-CoV-2 infection
An international team of scientists has developed an online tool for predicting recovery from COVID-19, based on an array of complex biological signatures. Their approach could pave the way for a better understanding of the molecular mechanisms underpinning long COVID Initial research on SARS-CoV-2 focussed on the immune response to the virus in order to […]
Improving the diagnosis and monitoring of rare blood vessel disease
Two St Catharine’s Fellows are part of a team of scientists and doctors that showed for the first time that a new assessment tool holds major promise for diagnosing and monitoring large vessel vasculitis (LVV), a group of diseases that affect the body’s blood vessels. LVV is rare but causes chronic inflammation of the larger […]
Cambridge achievers recognised in New Year Honours
Economist Professor Sir Partha Dasgupta receives an elevated knighthood. Sir Partha, the Frank Ramsey Professor Emeritus of Economics, is made a Knight Grand Cross of the Order of the British Empire for services to economics and the natural environment. Another economist, Dr Graham Gudgin, of the Centre for Business Research, is awarded a CBE for services to economic […]
The off-patent drug that could protect us from future COVID-19 variants
Cambridge scientists have identified a drug that can be repurposed to prevent COVID-19 in research involving a unique mix of ‘mini-organs’, donor organs, animal studies and patients.
Blood thinning drug to treat recovery from severe COVID-19 is not effective
The HEAL-COVID trial (Helping to Alleviate the Longer-term consequences of COVID-19) is funded by the National Institute for Health and Care Research (NIHR) and the Cambridge NIHR Biomedical Research Centre. To date, more than a thousand NHS patients hospitalised with COVID have taken part in HEAL-COVID, a platform trial that is aiming to find treatments […]
‘Programmable molecular scissors’ could help fight COVID-19 infection
Enzymes are naturally occurring biological catalysts, which enable the chemical transformations required for our bodies to function – from translating the genetic code into proteins, right through to digesting food. Although most enzymes are proteins, some of these crucial reactions are catalysed by RNA, a chemical cousin of DNA, which can fold into enzymes known […]
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