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Department of Medicine

Read more at: Hydrogen sulfide signalling: new analytical tools and therapeutic perspectives

Hydrogen sulfide signalling: new analytical tools and therapeutic perspectives

10 December 2025

In a study led by Dr Jan Miljkovic and Professor Mike Murphy in Nature Communications, the team has developed a highly sensitive LC–MS/MS workflow that captures the sulfur atom of H₂S and the terminal sulfur atoms of RSS⁻ and RS(S)ₙS⁻ as diagnostic products in complex biological samples.


Read more at: Largest study of nose microbiome helps highlight those at risk of Staph aureus infection
an electron micrograph of S. aureus (credit: David Goulding - Wellcome Sanger Institute)

Largest study of nose microbiome helps highlight those at risk of Staph aureus infection

4 December 2025

A study of the human nasal microbiome by Ewan Harrison, Sharon Peacock and colleagues has allowed scientists to rethink how bacterial communities interact in the nose. People who persistently carry Staphylococcus aureus ( S. aureus ) in their nose have fewer species of other bacteria, while certain bacteria may help to...


Read more at: Bacteria tune their membranes to manage energy and resist drugs
Image of Escherichia coli

Bacteria tune their membranes to manage energy and resist drugs

1 December 2025

New research led by the Universities of Cambridge and Basel shows how bacteria regulate membrane channels to control nutrient flow and antibiotic uptake, revealing a hidden mechanism of drug resistance. A new study in Nature Microbiology , co-led by Professor Andres Floto at the Victor Phillip Dahdaleh Heart & Lung...


Read more at: Bird flu viruses are resistant to fever, making them a major threat to humans

Bird flu viruses are resistant to fever, making them a major threat to humans

28 November 2025

In a study published today in Science, Professor Sam Wilson and colleagues identified a gene that plays an important role in setting the temperature sensitivity of a virus. In the deadly pandemics of 1957 and 1968, this gene transferred into human flu viruses, and the resulting virus thrived.


Read more at: Professor James Rudd receives funding for cutting-edge AI health research

Professor James Rudd receives funding for cutting-edge AI health research

27 November 2025

Professor James Rudd has received new research funding from the Accelerate Programme for Scientific Discovery and the Cambridge Centre for Data-Driven Discovery for a groundbreaking project developing a coronary artery CT foundation model to improve early detection of high-risk heart disease.


Read more at: AI tool spots blood cell abnormalities missed by doctors

AI tool spots blood cell abnormalities missed by doctors

20 November 2025

Professor Michael Roberts (Department of Applied Mathematics and Theoretical Physics & Department of Medicine) and colleagues has developed CytoDiffusion, an AI tool that detects subtle blood cell abnormalities that clinicians may miss. This could change the way conditions such as leukaemia are diagnosed.


Read more at: Advancing typhoid vaccine in Africa

Advancing typhoid vaccine in Africa

14 November 2025

Cambridge, Seoul and Ghana are working together to bring life-saving solutions across the continent to communities at risk.


Read more at: Risk of rare heart complications in children higher after COVID-19 infection than after vaccination

Risk of rare heart complications in children higher after COVID-19 infection than after vaccination

6 November 2025

Children and young people faced long-lasting and higher risks of rare heart and inflammatory complications after COVID-19 infection, compared to before or without an infection, according to new research. Meanwhile COVID-19 vaccination was only linked to a short-term higher risk of myocarditis and pericarditis.


Read more at: Stopping cancer before it starts: the Cambridge venture redefining age-related disease prevention
Photo of Elena's group at PVCC

Stopping cancer before it starts: the Cambridge venture redefining age-related disease prevention

5 November 2025

Ahead of the Grand Finale of this year’s Postdoc Venture Creation Challenge , we spoke with Dr Elena Pavlova , the scientist-turned-founder behind Protalea Bio, one of this year’s standout finalists aiming to stop age-related diseases like cancer and neuroinflammation before they start. At the heart of Protalea Bio’s...


Read more at: Early Crohn's treatment 'could save NHS millions'

Early Crohn's treatment 'could save NHS millions'

29 October 2025

Dr Nuru Noor, Prof Miles Parkes, and colleagues from Cambridge found using biologic drugs like Infliximab soon after diagnosis, rather than when symptoms worsen, was five times more effective at controlling the disease.


Researchers in the news

Ravi Gupta (CITIID) speaks to New Scientist about a person who was left HIV-free after a transplant of non-HIV resistant stem cells.


Miles Parkes and Nuru Noor (Medicine) led a study which showed that using biologic drugs soon after a diagnosis of Crohn's disease, rather than when symptoms worsen, is five times more effective at controlling the disease, as reported by the BBCRead more on the CUH website.


Clare Bryant (Medicine) spoke to the Financial Times about new research in which scientists have edited the genes of pigs to resist swine fever. She said that just as there is no will to vaccinate animals in some countries, there might also be reluctance to use gene editing.


Shuaib Nasser (Medicine) spoke to the Daily Mail about a new nasal spray developed to treat life-threatening allergic reactions that is now available in the UK, saying that its compactness and ease of use may make it more practical than current devices for administering adrenaline.


Sharon Peacock (PACE) appeared on the Naked Scientists Titans of Science podcast talking about her work on whole genome sequencing of pathogens such as MRSA and SARS CoV-2, and studies of antimicrobial resistance.


Mike Weekes (ImID) spoke to the Independent about the risks of warmer temperatures and altered rainfall patterns caused by climate change leading to a spread of tropical diseases to Europe and the UK.