Our Division has an international reputation in the research areas of atherosclerosis (arterial thickening), cardiovascular stem cells and vascular imaging. We use human and mouse cell models to study the role of specific gene products, cellular pathways and cell types in the progress of vascular disease. Our clinical research examines the utility of invasive and non-invasive imaging to predict events in patients, and novel therapeutics in patients with stable and unstable angina. Our Significant achievements include our identifying the role of acquired immunity in atherosclerosis, using stem cells to model genetic vascular disease, and the use of novel tracers and biomechanics to identify unstable plaques. To achieve these successes, we work with local research institutes and physical sciences departments, as well expanding our capabilities in the Heart and Lung Research Institute on Cambridge Biomedical Campus. In partnership with industry, our work also forms part of several multi-centre clinical trials, which enables us to translate our research findings into the clinic and improve patient welfare.