Herpesvirus are large DNA viruses which have co-evolved with their human and animal hosts for millions and millions of years. Humans are infected with eight different herpesviruses causing a broad spectrum of disease ranging from the common cold sores to cancer. Besides encoding for >100 viral proteins they also express numerous small and large non-protein-coding RNAs to reprogramme their host cell environement for their own needs. We aim to increase our understanding of the underlying molecular mechanisms and identify new molecular targets for antiviral intervention. [Read More…]
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