Smooth muscle cells created from patients’ skin cells

Researchers from the Division of Cardiovascular Medicine (Dr Sanjay Sinha and Ms Christine Cheung) and the Laboratory for Regenerative Medicine (Prof Roger Pedersen and Dr Andreia Bernardo) have for the first time been able to reproduce three of the major embryonic developmental pathways for vascular smooth muscle cells (SMCs) in the culture dish. This system will allow the investigators to study how SMC origin affects development of vascular disease, to model genetic vascular diseases such as Marfans syndrome and represents an important step … [Read More...]