Genome-wide CRISPR/Cas9 deletion screen defines mitochondrial gene essentiality and novel routes for tumour cell viability in hypoxia. Thomas LW, Esposito E, Morgan RE, Price S, Young J, Williams SP, Maddalena LA, McDermott U, and Ashcroft M. Communications Biology. 2021 May 21;615:4. doi: 10.1038/s42003-021-02098-x.

CHCHD4 (MIA40) and the mitochondrial disulfide relay system.  Al-Habib H, Ashcroft M.Biochem Soc Trans. 2021 Feb 26;49(1):17-27. doi: 10.1042/BST20190232.PMID: 33599699

CHCHD4 regulates tumour proliferation and EMT-related pheotypes, through respiratory chain-mediate metabolism. Thomas LW, Esposito C, Stephen JM, Costa ASH, Frezza C, Blacker TS, Szabadkai G, Ashcroft M. Cancer Metab. 2019 Jul 16;7:7. doi: 10.1186/s40170-019-0200-4.

Exploring the molecular interface between hypoxia-inducible factor signalling and mitochondria.  Thomas LW, Ashcroft M.  Cell Mol Life Sci. 2019 May;76(9):1759-1777. doi: 10.1007/s00018-019-03039-y.

CHCHD4 confers metabolic vulnerabilities to tumour cells through its control of the mitochondrial respiratory chain.  Thomas LW, Stephen JM, Esposito C, Hoer S, Antrobus R, Ahmed A, Al-Habib H, Ashcroft M.  Cancer Metab. 2019 Mar 6;7:2. doi: 10.1186/s40170-019-0194-y.

VHL-mediated regulation of CHCHD4 and mitochondrial function. Briston T., Stephen J., Thomas L.W., Esposito C., Chung Y.L., Syafruddin S., Turmaine M., Maddalena L., Greef B., Szabadkai G., Maxwell P.H., Vanharanta S. and Ashcroft M. Front Oncology (2018) 8: 388.

CHCHD4 regulates intracellular oxygenation and perinuclear distribution of mitochondria. Thomas L.W., Staples O., Turmaine M., Ashcroft M. Frontiers in Oncology (2017) 7: 71.

HIF-1alpha localization with mitochondria: A new role for an old favorite? Briston, T., Yang J., Ashcroft M. Cell Cycle (2011) 10: 4170-4171.