The NECS Respiratory Medicine group comprises respiratory research groups from four outstanding research environments, Newcastle, Edinburgh, Sheffield and Cambridge. Our aims are to promote and support research into respiratory disease, and foster collaborations between our institutes. All centres have extensive experience in basic science, translational and clinical respiratory research.
The Respiratory Medicine Division at the University of Cambridge has research interests in granulocyte cell biology and trafficking, the genetic and molecular basis of pulmonary hypertension, oxygen sensing, genetics/genomics of bacterial infections, cystic fibrosis and non-CF bronchiectasis, innate immunity, lung injury and the molecular mechanisms of ER stress and ubiquitination.
- Edwin Chilvers, Professor of Respiratory Medicine and Head of Division.
- Nick Morrell, BHF Professor of Cardiopulmonary Medicine
- Andre Floto, Professor of Respiratory Cell Biology
- Professor of Respiratory Science-TBA
- Stefan Marciniak, MRC Senior Clinical Fellow
- James Nathan, Wellcome Trust Senior Clinical Research Fellow
- Charlotte Summers, University Lecturer
- Andrew Cowburn, Senior Research Associate
- Paul Upton, Senior Research Associate
- Neda Farahi, Senior Research Associate
- Li Wei, BHF Lecturer in Structural Biology
- Amer Rana, BHF Lecturer in Regenerative Medicine
Respiratory Medicine is the largest grouping within the MRC Centre for Inflammation Research, with close ties to the MRC Centre for Regenerative Medicine and to the EPSRC-MRC Centre for Optical Imaging. Our core research interests are in inflammation resolution in the context of lung injury and in tissue repair, translated to diseases including COPD, pulmonary fibrosis and acute lung injury and to children with asthma and with severe RSV infection.
- Moira Whyte, Professor of Respiratory Medicine, Director of the MRC Centre for Inflammation Research
- Chris Haslett, Sir John Crofton Professor of Respiratory Medicine, Director of The Queen’s Medical Research Institute
- Jurgen Schwarze, Professor of Child Life and Health
- Adriano Rossi, Professor of Respiratory and Inflammation Pharmacology
- Ian Dransfield, Professor of Leukocyte and Lung Cell Biology
- Sarah Walmsley, Reader in Respiratory Medicine and Wellcome Senior Clinical Fellow
- Donald Davidson, Senior Lecturer and MRC Senior Clinical Fellow
- Nik Hirani, Senior Clinical Lecturer and Clinical Lead for Respiratory Medicine
- Kev Dhaliwal, Senior Clinical Lecturer in Respiratory Medicine
- Marc Vendrell, Lecturer
- Sonia Vermeren, Chancellors Fellow
- Steve Jenkins, Chancellors Fellow and MRC New Investigator
- Henry McSorley, Chancellors Fellow
- Chengcan Yao, Chancellors Fellow
The University of Sheffield
Sheffield has an excellent track record of securing clinical research fellowships from PhD level to Senior Clinical Fellowships. Our expertise is predominantly in innate immunity, airway epithelium, immunodeficiency and host-pathogen interactions, with a particular focus on the biology of the neutrophil and macrophage and their roles in lung disease. We have developed innovative models of inflammation in vivo enabling the visualisation of cellular and subcellular events as inflammation progresses and resolves. Excellent opportunities exist at the interface with microbiology, particularly in staphylococcal and streptococcal diseases. We promote highly translational research, for example using human models of inflammation induced by endotoxin challenge, and expertise is also strong in practical applied clinical health services research. Sheffield is a National Centre for pulmonary arterial hypertension, with extensive research in basic and clinical science, and additionally has a programme based on novel imaging modalities, particularly MRI techniques to visualise lung structure, function, ventilation and perfusion.
- Ian Sabroe, Professor of Inflammation Biology, co-director of Medical Humanities Sheffield
- Alison Condliffe, Professor of Respiratory Medicine
- Stephen Renshaw, Professor of Respiratory Medicine
- David Dockrell, Professor of Infectious Diseases
- Jim Wild, Professor of Magnetic Resonance Physics and NIHR Research Professor in Pulmonary Imaging
- David Kiely, Honorary Professor of Pulmonary Vascular Diseases
- Dr Colin Bingle, Reader in Respiratory Medicine
- Dr Allan Lawrie, BHF Senior Fellow
- Dr Lynne Prince, Russell Fellow
- Dr Lisa Parker, Lecturer in Respiratory Medicine
- Dr Helen Marriott, Lecturer in Respiratory Medicine
- Dr Martin Wildman, Consultant in Cystic Fibrosis
Newcastle has a strong emphasis on translational respiratory research, complemented by a programme of basic science. The principal areas of interest are in pulmonary hypertension, lung transplantation, cellular innate immune biology in critically ill patients, bronchiectasis (cystic fibrosis and non-CF bronchiectasis), pulmonary fibrosis, and the biology of primary airway epithelial cells. The research portfolio spans multicentre randomised controlled trials led from Newcastle, experimental medicine studies (a) in healthy volunteers and (b) ex vivo lung perfusion using explanted human lungs, and basic science studies (with a distinct emphasis on primary human cells).
- Prof Paul Corris, Professor of Thoracic Medicine
- Prof John Simpson, Professor of Respiratory Medicine
- Prof Andy Fisher, Professor of Respiratory Transplant Medicine
- Dr Tony De Soyza, Senior Clinical Lecturer in Respiratory Medicine
- Dr Chris Ward, Senior Lecturer in Respiratory Medicine
- Dr Malcolm Brodlie, MRC Clinician Scientist and Clinical Senior Lecturer
- Dr Lee Borthwick, Research Fellow
- Dr James Garnett, Faculty Fellow
- Dr Anthony Rostron, Academic Clinical Lecturer
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NECS Research Meeting
Annual meetings are held to present current research projects and foster new collaborations.
Date of next meeting – TBC