Trembath RC, Thomson JR, Machado RD, Morgan NV, Atkinson C, Winship I, Simonneau G, Galie N, Loyd JE , Humbert M, Nichols WC, Morrell NW Clinical and molecular genetic features of pulmonary hypertension in hereditary hemorrhagic telangiectasia N Engl J Med 2001; 345: 325-334

Morrell NW, Yang X, Upton PD, Jourdan KB, Morgan N, Sheares KK, Trembath RC Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to TGFbeta-1 and bone morphogenetic proteins Circulation 2001; 104: 790-795

Atkinson C, Stewart S, Upton PD, Machado R, Thomson J, Trembath RC, Morrell NW Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of BMPR-II Circulation 2002; 105: 1672-1678

Rudarakanchana N, Flanagan JA, Chen H, Upton PD, Machado R, Patel D, Trembath RC, Morrell NW Functional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertension Hum Mol Genetics 2002; 11: 1517-25

Yang X, Long L, Southwood M, Rudarakanchana N, Upton PD, Jeffery TK, Atkinson C, Chen H, Trembath RC, Morrell NW Dysfunctional Smad signaling contributes to abnormal smooth muscle cell proliferation in familial pulmonary arterial hypertension Circulation Research 2005; 96: 1053-1063

Long L, MacLean M, Jeffery TK, Morecroft I, Yang X, Rudarakanchana N, Southwood M, James V, Trembath RC, Morrell NW Serotonin increases susceptibility to pulmonary hypertension in BMPR2 deficient mice Circulation Research 2006; 98: 818-827

Hansmann G, de Jesus Perez VA, Alastalo TP, Alvira CM, Guignabert C, Bekker JM, Schellong S, Urashima T, Wang L, Morrell NW, Rabinovitch M An antiproliferative BMP-2/PPARγ /apoE axis in human and murine SMCs and its role in pulmonary hypertension J Clin Invest 2008; 118: 1846-57

Yang J, Davies RJ, Southwood M, Long L, Yang X, Sobolewski A, Upton PD, Trembath RC, Morrell NW Mutations in bone morphogenetic protein type II receptor cause dysregulation of Id gene expression in pulmonary artery smooth muscle cells: implications for familial pulmonary arterial hypertension Circulation Research 2008; 102: 1212-21

Sobolewski A, Rudarakanchana N, Upton PD, Yang J, Crilley TK, Trembath RC, Morrell NW Failure of bone morphogenetic protein receptor trafficking in pulmonary arterial hypertension: potential for rescue Hum Mol Genet 2008;17: 3180-90

Long L, Crosby A, Yang X, Southwood M, Upton PD, Kim DK, Morrell NW Altered bone morphogenetic protein and transforming growth factor-beta signaling in rat models of pulmonary hypertension: potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease Circulation 2009; 119: 566-76

Upton PD, Davies RJ, Trembath RC, Morrell NW Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells J Biol Chemistry 2009; 284: 15794-804

Toshner M, Voswinckel R, Southwood M, Al-Lamki R, Howard LS, Marchesan D, Yang J, Suntharalingam J, Soon E, Exley A, Stewart S, Hecker M, Zhu Z, Gehling U, Seeger W, Pepke-Zaba J, Morrell NW Evidence of dysfunction of endothelial progenitors in pulmonary arterial hypertension. Am J Respir Crit Care Med;180: 780-787

Cannon JE, Upton PD, Smith JC, Morrell NW Intersegmental vessel formation in zebrafish: requirement for VEGF but not BMP signalling revealed by selective and non-selective BMP antagonists Br J Pharmacol 2010;161: 140-9

Yang J, Li X, Al-Lamki RS, Southwood M, Zhao J, Lever AM, Grimminger F, Schermuly RT, Morrell NW Smad-dependent and Smad-independent induction of ld1 by prostacyclin analogues inhibits proliferation of pulmonary artery smooth muscle cells in vitro and in vivo Circulation Research 2010;107:252-62.

Durrington HJ, Upton PD, Hoer S, Boname J, Dunmore BJ, Yang J, Crilley TK, Butler LM, Blackbourn DJ, Nash GB, Lehner PJ, Morrell NW Identification of a lysosomal pathway regulating degradation of the bone morphogenetic protein receptor type II J Biol Chemistry 2010;285:37641-9.

Ghofrani HA, Morrell NW, Hoeper MM, Olschewski H, Peacock AJ, Barst RJ, Shapiro S, Golpon H, Toshner M, Grimminger F, Pascoe S. Imatinib in pulmonary arterial hypertension patients with inadequate response to established therapy. Am J Respir Crit Care Med. 2010;182:1171-7.

Soon E, Holmes AM, Treacy CM, Doughty NJ, Southgate L, Machado RD, Trembath RC, Jennings S, Barker L, Nicklin P, Walker C, Budd DC, Pepke-Zaba J, Morrell NW. Elevated levels of inflammatory cytokines predict survival in idiopathic and familial pulmonary arterial hypertension. Circulation. 2010;122:920-7.

Davies RJ, Holmes AM, Deighton J, Long L, Yang X, Barker L, Walker C, Budd DC, Upton PD, Morrell NW. BMP type II receptor deficiency confers resistance to growth inhibition by TGF-β in pulmonary artery smooth muscle cells: role of proinflammatory cytokines. Am J Physiol Lung Cell Mol Physiol. 2012;302(6):L604-15.
Ormiston ML, Chang C, Long LL, Soon E, Jones D, Machado R, Treacy C, Toshner MR, Campbell K, Riding A, Southwood M, Pepke-Zaba J, Exley A, Trembath RC, Colucci F, Wills M, Trowsdale J, Morrell NW. Impaired natural killer cell phenotype and function in idiopathic and heritable pulmonary arterial hypertension. Circulation. 2012;126(9):1099-109.

 Yang J, Li X, Al-Lamki RS, Wu C, Weiss A, Berk J, Schermuly RT, Morrell NW. Sildenafil potentiates bone morphogenetic protein signaling in pulmonary arterial smooth muscle cells and in experimental pulmonary hypertension. Arterioscler Thromb Vasc Biol. 2013 Jan;33(1):34-42.

Geti I, Ormiston ML, Rouhani F, Toshner M, Movassagh M, Nichols J, Mansfield W, Southwood M, Bradley A, Rana AA, Vallier L, Morrell NW. A practical and efficient cellular substrate for the generation of induced pluripotent stem cells from adults: blood-derived endothelial progenitor cells. Stem Cells Transl Med. 2012 Dec;1(12):855-65. doi: 10.5966/sctm.2012-0093. Epub 2012 Nov 29.