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Clement, M.*/Chappell, J.*, Raffort, J., Lareyre, F., Vandestienne, M., Taylor, A.L., Finigan, A., Harrison, J, Bennett, M.R., Taleb,S., Jorgensen, H.F.#/Mallat, Z#. Vascular Smooth Muscle Cell Plasticity and Autophagy in Dissecting Aortic Aneurysms. *Joint first authors. #Joint last authors. ATVB, Online Ahead of Print. https://doi.org/10.1161/ATVBAHA.118.311727.
Dobnikar, L.*/Taylor, A.L.*, Chappell, J., Oldach, P., Harman, J.L., Oerton, E., Dzierzak, E., Bennett, M.R., Spivakov, M.#/Jørgensen, H.F.# (2018). Disease-relevant transcriptional signatures identified in individual smooth muscle cells from healthy mouse vessels. Nature Communications, 9, 4567. *Joint first authors. #Joint last authors.
Tomaz, R.A., Harman, J.L., Karimlou, D., Weavers, L., Fritsch, L., Bou-Kheir, T., Bell, E., Torres, I.D.V., Niakan, K.K., Fisher, C., Joshi O., Stunnenberg H.G., Curry E., Ait-Si-Ali S., Jørgensen H.F., Azuara V. (2017). Jmjd2c/Kdm4c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation. Development, 144, 567-79.
Chappell, J., Harman, J.L., Narasimhan, V.M., Yu, H., Foote, K., Simons, B.D., Bennett, M.R., and Jørgensen, H.F. (2016). Extensive Proliferation of a Subset of Differentiated, yet Plastic, Medial Vascular Smooth Muscle Cells Contributes to Neointimal Formation in Mouse Injury and Atherosclerosis Models. Circulation Research, 119, 1313–1323.
Masserdotti G., Gillotin S., Sutor B., Drechsel D., Irmler M., Jørgensen H.F., Sass S., Theis F.J., Beckers J., Berninger B., Guillemot F., Götz M. (2015). Transcriptional Mechanisms of Proneural Factors and REST in Regulating Neuronal Reprogramming of Astrocytes. Cell Stem Cell, 17:74-88.
Arnold P., Schöler A., Pachkov M., Balwierz P., Jørgensen H., Stadler M.B., van Nimwegen E., Schübeler D. (2013). Modeling of epigenome dynamics identifies transcription factors that mediate Polycomb targeting. Genome Res, 23, 60-73.
Mazzarella, L.*/Jørgensen, H.F.*, Terry, A., Kouskoff V., Merkenschlager M., Fisher, A.G. (2011). Embryonic stem cell-derived hemangioblasts remain epigenetically plastic and require PRC1 to prevent neural gene expression. Blood, 117: 83-87. *Joint first authors.
Jørgensen, H.F., Fisher, A.G. (2010). Can controversies be put to REST? Nature, 467: E3-4.
Jørgensen, H.F., Chen, Z.-F., Merkenschlager, M., Fisher, A.G. (2009). Is REST required for ESC pluripotency? Nature, 457, E4-5.
Jørgensen, H.F., Terry, A., Beretta, C., Peirera, C.F., LeLeu, M., Chen, Z.-F., Merkenschlager, M., Fisher, A.G. (2009). REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells. Development, 136, 715-21.
Jørgensen, H.F., Fisher, A.G. (2009). LOCKing in Cellular Potential. Cell Stem Cell, 4:192-4.
Illingworth R., Kerr A., DeSousa D., Jørgensen H., Ellis P., Stalker J., Jackson D., Clee C., Plumb R., Jane Rogers J., Humphray S., Cox T., Langford C., Bird A. (2008). A novel CpG island set identifies tissue-specific methylation at developmental gene loci. PLoS Biology 6, e22.
Jørgensen, H.F., Azuara, V., Amoils, S., Spivakov, M., Terry, A., Nesterova, T., Cobb, B.S., Ramsahoya, B., Merkenschlager, M., Fisher, A.G. (2007). The impact of chromatin modifiers on the timing of locus replication in mouse embryonic stem cells. Genome Biology 8, R169.
Jørgensen, H. F., Giadrossi, S., Casanova, M., Endoh, M., Koseki, H., Brockdorff, N., and Fisher, A. G. (2006). Stem cells primed for action: polycomb repressive complexes restrain the expression of lineage-specific regulators in embryonic stem cells. Cell Cycle 5, 1411-4.
Azuara, V., Perry, P., Sauer, S., Spivakov, M., Jørgensen, H. F., John, R. M., Gouti, M., Casanova, M., Warnes, G., Merkenschlager, M., and Fisher, A. G. (2006). Chromatin signatures of pluripotent cell lines. Nat Cell Biol 8, 532-8.
Jørgensen, H. F., Adie, K., Chaubert, P., and Bird, A. P. (2006). Engineering a high-affinity methyl-CpG-binding protein. Nucleic Acids Res 34, e96.
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Jørgensen, H. F., and Bird, A. (2002). MeCP2 and other methyl-CpG binding proteins. Ment Retard Dev Disabil Res Rev 8, 87-93.
Prokhortchouk, A., Hendrich, B., Jørgensen, H., Ruzov, A., Wilm, M., Georgiev, G., Bird, A., and Prokhortchouk, E. (2001). The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor. Genes Dev 15, 1613-8.
Talukder, A. H., Jørgensen, H. F., Mandal, M., Mishra, S. K., Vadlamudi, R. K., Clark, B. F., Mendelsohn, J., and Kumar, R. (2001). Regulation of elongation factor-1alpha expression by growth factors and anti-receptor blocking antibodies. J Biol Chem 276, 5636-42.
Bischoff C., Kahns S., Lund A., Jørgensen H. F., Praestegaard M., Clark B. F., Leffers H. (2000). The human elongation factor 1 A-2 gene (EEF1A2): complete sequence and characterization of gene structure and promoter activity. Genomics 68, 63-70.
Nordhoff E., Krogsdam A. M., Jorgensen H. F., Kallipolitis B. H., Clark B. F., Roepstorff P., Kristiansen K. (1999). Rapid identification of DNA-binding proteins by mass spectrometry. Nat Biotechnol 17, 884
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