Dr James Nathan is a Wellcome Trust Senior Clinical Research Fellow and Honorary Consultant in Respiratory Medicine at the University of Cambridge. He graduated from the University of Bristol and undertook his specialist clinical training in Cambridge. Upon award of a Wellcome Trust Clinical Training Fellowship in 2005, he conducted his thesis research in Paul Lehner’s group, exploring the regulation of ubiquitin E3 ligases. James then joined the laboratory of Alfred Goldberg at Harvard University with an MRC Clinician Scientist Award, investigating mechanisms of proteasome regulation and ubiquitin chain selectivity. In 2014, he established his independent laboratory in the Cambridge Institute for Medical Research, exploring how proteins are selectively targeted for degradation by the ubiquitin proteasome system, with a particular focus on the hypoxia response and oxygen sensing.
The Lister Institute Research Prize Fellowships are one-off awards which seek to help support and nurture future leaders of biomedical research by providing £200,000 (or equivalent euros) which may be used in any appropriate way to support the holder’s research, other than the provision or augmentation of personal salary, over a period of up to five years. The awards are aimed at younger, rather than established, researchers who might be in their early years of running their own groups and for whom receipt of the Prize would ‘make a real difference’.