Congratulations and well done to Dr Jenna Stephen and Dr Hasan Al-Habib, who were each awarded their PhD during the recent University graduation ceremonies at the Senate House.
UKRI Policy Internship
Hasan Al-Habib, a final year MRC-DTP student supervised by Prof Ashcroft has been offered a competitive UKRI Policy Internship after being interviewed for the 2021/2022 round.
Review published October 22, 2021
Review published in Frontiers in Cell and Developmental Biology (Signaling Section), entitled ‘The Contextual Essentiality of Mitochondrial Genes in Cancer, by Luke William Thomas, Margaret Ashcroft. DOI: 10.3389/fcell.2021.695351
Paper Accepted April 13, 2021
Research paper accepted in principle (Jan 20, 2021), has been fully accepted for publication in Nature Communications Biology. Luke Thomas, Cinzia Esposito et al and Margaret Ashcroft. Genome-wide CRISPR/Cas9 deletion screen defines mitochondrial gene essentiality and identifies routes for tumour cell viability in hypoxia.
Review Accepted January 6, 2021
Review accepted in Biochemical Society Transactions. Hasan Al-Habib and Margaret Ashcroft. CHCHD4 (MIA40) and the mitochondrial disulfide relay system (https://doi.org/10.1042/BST20190232).
Ashcroft Lab Opens June 15-July 2020
Delighted the Ashcroft lab opens after lockdown, and group adjusting excellently to working differently due to COVID restrictions and social distancing.
Ashcroft Lab Closure March 20, 2020
Due to the COVID pandemic, the Ashcroft lab closed and the group continued to work remotely and meet virtually. During lockdown, Basma Greef was seconded to NHS clinical duties; Hasan Al-Habib worked with the COVID testing programme; Lucas Maddalena returned to Canada.
Keystone Hypoxia Meeting January 19-23, 2020
Prof Ashcroft was invited to speak at the Keystone meeting on Hypoxia: Molecules, Mechanisms and Disease (Colorado, USA), and gave a talk entitled ‘The Redox-Regulated Disulphide Relay System Controls Hypoxia Responses’, presenting work from the group including Hasan Al-Habib.
Keynote Lecture
Prof Ashcroft gave the Keynote Lecture, entitled ‘Mitochondria and Hypoxia Signalling’ at the 2nd Mitochondrial Biology and Toxicology Research day hosted by the Cambridge Alliance on Medicines Safety (CAMS) and organised jointly by AstraZeneca, GSK and the MRC
Scientific Symposium on Mitochondrial Biology
Prof Ashcroft attended the 1st ‘MITOchats’ Summer Symposium at the Max Planck Institute for Biology and Ageing in Cologne, Germany (http://sfb1218.uni-koeln.de/mitochats_2019symposium.html). Prof Ashcroft gave an invited talk entitled ‘Mitochondria and Hypoxia Signalling’. MITOchats was an excellent symposium with talks from outstanding international speakers.